A Study of Some Cellulose Derivatives As Hydrogel For Control Drug Release

Neutral and semi-synthetic hydrophilic polymers are widely used in pharmaceutical technology to fomlUlate as controlled release drugs delivery systems ,cellulose derivatives is biocompatibilily, biodegradability , non-toxicity, its is a good candidate as drug copyright.In this study, polymers were used as cellulose derivatives like Methylcellulose (MC) & Soditun Carboxymetl1ylcellulose (NaCMC) as hydrogels Power Supply for controlled delivery for two kinds of drugs, Cefotaxine & Amoxycill ine trihydrate i n different media (Distilled water, Normal Saline & Buffer Mirror Hardware solution PH=2).It has been shown that for sodium Carboxymethylcellulnse the drug release rate is more than the Mcthylcellulose and that the release rate for Amoxycilli ne trihydratc is more than Cefotaxine.